Yang Zhao Selected Research

Tyrosine Kinase Inhibitors

2/2022	Clinical outcomes of advanced non-small cell lung cancer patients harboring distinct subtypes of EGFR mutations and receiving first-line tyrosine kinase inhibitors: brain metastasis and de novo T790M matters.
1/2022	Overall survival benefit of osimertinib and clinical value of upfront cranial local therapy in untreated EGFR-mutant nonsmall cell lung cancer with brain metastasis.
11/2021	Clinical Value of Upfront Cranial Radiation Therapy in Osimertinib-Treated Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer With Brain Metastases.
1/2021	c-Src Increases the Sensitivity to TKIs in the EGFR-Mutant Lung Adenocarcinoma.
12/2020	Survival outcomes and symptomatic central nervous system (CNS) metastasis in EGFR-mutant advanced non-small cell lung cancer without baseline CNS metastasis: Osimertinib vs. first-generation EGFR tyrosine kinase inhibitors.
12/2020	A narrative review of evolving roles of radiotherapy in advanced non-small cell lung cancer: from palliative care to active player.
1/2020	Cardiovascular mortality among chronic myeloid leukemia patients in the pre-tyrosine kinase inhibitor (TKI) and TKI eras: a surveillance, epidemiology and end results (SEER) analysis.
11/2018	Effect of Anlotinib as a Third-Line or Further Treatment on Overall Survival of Patients With Advanced Non-Small Cell Lung Cancer: The ALTER 0303 Phase 3 Randomized Clinical Trial.
1/2017	Clinical outcomes of epidermal growth factor receptor tyrosine kinase inhibitors in recurrent adenosquamous carcinoma of the lung after resection.

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Yang Zhao Research Topics

Disease

319	Neoplasms (Cancer) 08/2022 - 03/2008
62	Neoplasm Metastasis (Metastasis) 08/2022 - 12/2006
54	Breast Neoplasms (Breast Cancer) 05/2022 - 04/2008
48	Carcinogenesis 08/2022 - 04/2010
41	Inflammation (Inflammations) 07/2022 - 11/2010
35	Infections 05/2022 - 03/2009
32	Hypertension (High Blood Pressure) 05/2022 - 01/2013
31	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2022 - 12/2009
30	Type 2 Diabetes Mellitus (MODY) 02/2022 - 07/2007
26	Lung Neoplasms (Lung Cancer) 01/2022 - 02/2010
26	Pain (Aches) 09/2021 - 11/2010
25	Carcinoma (Carcinomatosis) 08/2020 - 07/2011
24	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 03/2006
23	COVID-19 06/2022 - 01/2020
23	Ovarian Neoplasms (Ovarian Cancer) 11/2021 - 03/2010
22	Psoriasis (Pustulosis Palmaris et Plantaris) 05/2022 - 03/2015
21	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 11/2002
19	Stomach Neoplasms (Stomach Cancer) 06/2022 - 04/2008
19	Hypoxia (Hypoxemia) 04/2022 - 06/2013
18	Body Weight (Weight, Body) 01/2022 - 01/2010
17	Prostatic Neoplasms (Prostate Cancer) 08/2022 - 01/2010
17	Obesity 10/2021 - 06/2009
16	Insulin Resistance 02/2022 - 07/2010
16	Ovarian Epithelial Carcinoma 01/2018 - 10/2009
15	Ischemia 04/2021 - 01/2013
14	Fibrosis (Cirrhosis) 01/2022 - 02/2012
13	Cardiovascular Diseases (Cardiovascular Disease) 06/2022 - 06/2009
12	Major Depressive Disorder (Major Depressive Disorders) 01/2022 - 12/2010
11	Osteoarthritis 02/2022 - 04/2011
11	Adenocarcinoma 01/2022 - 01/2012
11	Neuralgia (Stump Neuralgia) 01/2021 - 11/2010
10	Endometrial Neoplasms (Endometrial Cancer) 07/2022 - 01/2016
10	Cataract (Cataracts) 05/2022 - 09/2016
10	Adenocarcinoma of Lung 01/2022 - 04/2010
10	Autoimmune Diseases (Autoimmune Disease) 12/2020 - 09/2015
9	Wounds and Injuries (Trauma) 04/2022 - 02/2013
9	Reperfusion Injury 01/2022 - 08/2014
9	Necrosis 01/2022 - 01/2015
9	Lymphatic Metastasis 09/2021 - 02/2010
9	Edema (Dropsy) 09/2021 - 09/2011
9	Asthma (Bronchial Asthma) 03/2021 - 06/2011
9	Sepsis (Septicemia) 01/2021 - 11/2012
9	Atherosclerosis 01/2021 - 09/2009
8	Hypersensitivity (Allergy) 07/2022 - 01/2010
8	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 05/2022 - 01/2017
8	Parkinson Disease (Parkinson's Disease) 04/2022 - 01/2016
8	Hemorrhage 01/2022 - 02/2012
8	Myocardial Infarction 01/2022 - 08/2015
8	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2021 - 12/2012
7	Glioma (Gliomas) 10/2022 - 06/2013

Drug/Important Bio-Agent (IBA)

118	Proteins (Proteins, Gene)FDA Link 10/2022 - 01/2005
69	Biomarkers (Surrogate Marker)IBA 05/2022 - 04/2008
50	Pharmaceutical PreparationsIBA 07/2022 - 04/2008
41	MicroRNAs (MicroRNA)IBA 06/2022 - 04/2010
40	Messenger RNA (mRNA)IBA 01/2022 - 03/2008
34	Biological ProductsIBA 08/2022 - 01/2011
27	CytokinesIBA 10/2022 - 06/2011
22	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 12/2012
21	Long Noncoding RNAIBA 01/2022 - 01/2014
20	EnzymesIBA 07/2021 - 09/2009
18	RNA (Ribonucleic Acid)IBA 08/2022 - 01/2014
18	LipidsIBA 07/2022 - 06/2011
17	Duloxetine Hydrochloride (Cymbalta)FDA Link 11/2012 - 11/2010
15	Transcription Factors (Transcription Factor)IBA 10/2021 - 05/2012
14	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 03/2010
14	Circular RNAIBA 11/2021 - 01/2017
14	Small Interfering RNA (siRNA)IBA 01/2018 - 03/2010
13	Therapeutic UsesIBA 05/2022 - 11/2016
13	Paclitaxel (Taxol)FDA LinkGeneric 05/2022 - 03/2012
13	Immune Checkpoint InhibitorsIBA 01/2022 - 09/2017
13	Peptides (Polypeptides)IBA 01/2022 - 10/2009
13	ORALIT (ORS)IBA 01/2022 - 10/2010
12	ErbB Receptors (EGF Receptor)IBA 10/2022 - 03/2014
12	Indicators and Reagents (Reagents)IBA 01/2022 - 01/2012
12	Triglycerides (Triacylglycerol)IBA 09/2021 - 01/2017
11	Cisplatin (Platino)FDA LinkGeneric 05/2022 - 03/2008
11	Estrogen ReceptorsIBA 05/2022 - 02/2013
11	Phosphotransferases (Kinase)IBA 02/2022 - 03/2010
11	CateninsIBA 01/2020 - 06/2013
10	Fluorouracil (Carac)FDA LinkGeneric 12/2021 - 03/2008
9	DNA (Deoxyribonucleic Acid)IBA 10/2022 - 05/2009
9	secukinumabIBA 03/2022 - 04/2016
9	Tyrosine Kinase InhibitorsIBA 02/2022 - 01/2017
9	Neuroprotective AgentsIBA 02/2022 - 01/2018
9	Adenosine Triphosphate (ATP)IBA 01/2022 - 03/2008
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 01/2012
9	LigandsIBA 01/2022 - 12/2015
9	AntigensIBA 01/2022 - 07/2011
9	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2021 - 01/2014
9	Opioid Analgesics (Opioids)IBA 01/2021 - 12/2010
8	CholesterolIBA 01/2022 - 05/2015
8	Cyclin D1IBA 01/2019 - 03/2006
8	Pregabalin (Lyrica)FDA Link 11/2012 - 04/2011

Therapy/Procedure

114	Therapeutics 03/2022 - 06/2006
33	Drug Therapy (Chemotherapy) 01/2022 - 04/2010
16	Radiotherapy 04/2022 - 01/2013
13	Immunotherapy 01/2022 - 01/2017
10	Ligation 01/2022 - 02/2012
10	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2021 - 03/2014
8	Transplantation 01/2022 - 10/2014